Storage of Red Blood Cells and Transfusion-Related Acute Lung Injury

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Storage of Red Blood Cells and Transfusion-Related Acute Lung Injury.

Transfusion-related acute lung injury (TRALI) is a major complication post-transfusion. A consensus definition of TRALI has been recently established to improve diagnosis but the pathogenesis of TRALI is yet to be understood. Although the antibody-mediated two-hit model of TRALI is the classical narrative, increasing evidence of the probable implications of prolonged storage of blood provides n...

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Transfusion-related acute lung injury in multiple traumatized patients

Background: Many of the multiple traumatized patients who refer to the hospital need transfusion. Transfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. In the article, we present a case of TRALI following transfusion of packed red blood cells Case Presentation: A 24 year old male referred to Shahid Beh...

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Transfusion related acute lung injury.

TRALI (Transfusion related acute lung injury) is a devastating complication of Blood transfusions or its components irrespective of the blood grouping and cross match, We report a case of a Philipino house wife who had blood transfusion for her vaginal lacerations and developed acute pulmonary edema immediately afterwards. Antigranulocyte antibodies were not found in the donors. The patient rec...

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Transfusion-related acute lung injury.

A 49 year-old man with a history of alcohol-induced cirrhosis presented for orthotopic liver transplantation. His medical history is remarkable for mild hypertension treated with metoprolol and aldactone; recent admissions for ascitic fluid drainage, spontaneous bacterial peritonitis and transient episodes of hepatic encephalopathy; and a prior history of an open cholecystectomy. His admission ...

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Transfusion-related acute lung injury.

Transfusion-related acute lung injury is a life-threatening complication of hemotherapy associated with the transfusion of plasma-containing blood products. It is characterized by acute respiratory distress, pulmonary edema and hypoxemia. Although its frequency is unknown, Food and Drug Administration data suggest that it is the third most common cause of transfusion-associated deaths, represen...

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ژورنال

عنوان ژورنال: Journal of Anesthesia & Critical Care: Open Access

سال: 2014

ISSN: 2373-6437

DOI: 10.15406/jaccoa.2014.01.00002